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alan wayne chla

View in PubMed, Feasibility of treating post-transplantation minimal residual disease in children with acute leukemia Biol Blood Marrow Transplant. 2013 Mar; 33(3):e19-22. View in PubMed, Catastrophic failures of freezing bags for cellular therapy products: description, cause, and consequences Cytotherapy. View in PubMed, Autologous hematopoietic stem-cell transplantation for children with acute myeloid leukemia in first or second complete remission: a prognostic factor analysis J Clin Oncol. View in PubMed, Characterization and treatment of chronic active Epstein-Barr virus disease: a 28-year experience in the United States Blood. View in PubMed, Pediatric large-volume leukapheresis: a single institution experience with heparin versus citrate-based anticoagulant regimens Transfusion. 2018 Feb; 65(2). 2012 Sep; 87(9):916-22. . Select two study versions to compare. Claim your profile ... Childrens Hospital Los Angeles. View in PubMed, Decitabine and Vorinostat with Chemotherapy in Relapsed Pediatric Acute Lymphoblastic Leukemia: A TACL Pilot Study Clin Cancer Res. Pasadena Magazine's 2016 Top Doctors issue recognizes more than 200 physicians with privileges to practice at Children’s Hospital Los Angeles, a top-r Alan S. Wayne, MD Director, Children’s Center for Cancer and Blood Diseases, Children’s Hospital Los Angeles Head, Division of Hematology, Oncology and Blood and Marrow Transplantation at the Keck School of Medicine of the University of Southern California (USC) Biol Blood Marrow Transplant. Kymriah (tisagenlecleucel) is a FDA-approved CD19+ targeted Chimeric Antigen Receptor (CAR) T-cell therapy. View in PubMed, Cells to prevent/treat relapse following allogeneic stem cell transplantation Hematology Am Soc Hematol Educ Program. USC Stem Cell Seminar: Alan Wayne, Children's Hospital Los Angeles—"The Development of cell-based therapies for the treatment of hematologic malignancies" Tuesday, September 22 at 11:00am to 12:00pm. 1997 Dec; 3(6):310-5. . View in PubMed, Is another antibody conjugate against ALL needed? Dr. Alan S Wayne is a Hematology / Oncology Specialist in Los Angeles, California. Dr. Alan Wayne is a pediatric hematologist-oncologist in Los Angeles, California. View in PubMed, Collaborative multicenter investigation of marrow transplantation for sickle cell disease: current results and future directions Biol Blood Marrow Transplant. 2011 Jun 02; 117(22):5835-49. . Before Your Visit Read more. View in PubMed, NCI first international workshop on the biology, prevention, and treatment of relapse after allogeneic hematopoietic stem cell transplantation: report from the committee on disease-specific methods and strategies for monitoring relapse following allogeneic stem cell transplantationpart II: chronic leukemias, myeloproliferative neoplasms, and lymphoid malignancies. 2021 Jan; 68(1):e28574. View in PubMed, Recipient T-cell immune reconstitution in X-linked SCID after haploidentical maternal bone marrow transplant Ann N Y Acad Sci. Search for more papers by this author View in PubMed, Domain II of Pseudomonas Exotoxin Is Critical for Efficacy of Bolus Doses in a Xenograft Model of Acute Lymphoblastic Leukemia Toxins (Basel). View in PubMed, Sibling stem cell donor experiences at a single institution Psychooncology. View in PubMed, NCI First International Workshop on the Biology, Prevention, and Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation: report from the Committee on Disease-Specific Methods and Strategies for Monitoring Relapse following Allogeneic Stem Cell TransplantationPart I: Methods, acute leukemias, and myelodysplastic syndromes. View in PubMed, Proceedings from the National Cancer Institute's Second International Workshop on the Biology, Prevention, and Treatment of Relapse After Hematopoietic Stem Cell Transplantation: part IIIPrevention and treatment of relapse after allogeneic transplantation. Los Angeles, CA 90027 • 323-660-2450, ©2021 Children's Hospital Los Angeles is a 501(c)(3) organization, “CAR-T Therapy has been called the most significant therapeutic advance in childhood leukemia in a generation.”, Spiritual Care and Clinical Pastoral Education, Anesthesiology and Critical Care Medicine, Cell Therapy Program - CAR T-cell Therapy. 2006 Aug; 160(8):818-22. . View in PubMed, Proceedings from the National Cancer Institute's Second International Workshop on the Biology, Prevention, and Treatment of Relapse after Hematopoietic Stem Cell Transplantation: Part IBiology of relapse after transplantation. 2000 Mar 15; 95(6):1918-24. . View in PubMed, A validated pediatric disease risk index for allogeneic hematopoietic cell transplantation Blood. View in PubMed, Hematopoietic stem cell donation in children: a review of the sibling donor experience J Psychosoc Oncol. 2010 Sep; 16(9):1187-211. . 2017; 6(1):1294368. . 2013 Feb 14; 121(7):1165-74. . View in PubMed, Barriers to bone marrow transplantation for sickle cell anemia Biol Blood Marrow Transplant. Alan S. Wayne, M.D. View in PubMed, Induction of Immune Response after Allogeneic Wilms' Tumor 1 Dendritic Cell Vaccination and Donor Lymphocyte Infusion in Patients with Hematologic Malignancies and Post-Transplantation Relapse Biol Blood Marrow Transplant. 2016 07; 38(5):345-9. . 2015 Jan 29; 125(5):784-92. . View in PubMed, Immunotherapy for pediatric leukemia Front Oncol. View in PubMed, Ancillary therapy and supportive care of chronic graft-versus-host disease: national institutes of health consensus development project on criteria for clinical trials in chronic Graft-versus-host disease: VAncillary Therapy and Supportive Care Working Group Report. Biol Blood Marrow Transplant. Lancet Haematol. . View in PubMed, Characterization of CD22 expression in acute lymphoblastic leukemia Pediatr Blood Cancer. Dr. Alan Wayne, CHLA speaks on stage during The T.J. Martell Foundation 43rd New York Honors Gala at Cipriani 42nd Street on October 15, 2018 in New York City. 2017 12 08; 2017(1):708-715. . View in PubMed, Bortezomib, Dexamethasone, Mitoxantrone, and Vinorelbine (BDMV): An Active Reinduction Regimen for Children With Relapsed Acute Lymphoblastic Leukemia and Asparaginase Intolerance J Pediatr Hematol Oncol. The Institute’s director is Alan S. Wayne, MD, who joined CHLA and the University of Southern California (USC) in July 2013. 2014 Apr 17; 123(16):2470-7. . 2017; 6(1):1400370. . 2018 Feb; 65(2). Director, Cancer and Blood Disease Institute; Head, Division of Hematology-Oncology View in PubMed, Integrin a6 mediates the drug resistance of acute lymphoblastic B-cell leukemia Blood. Biol Blood Marrow Transplant. 2005 Jul 20; 23(21):4735-41. . 1993 Jan; 28(1):72-5. . View in PubMed, Lymphocytic interstitial pneumonitis, elevated IgM concentration, and hepatosplenomegaly in ataxia-telangiectasia J Pediatr. 2013 Dec; 19(12):1661-9. . 2010 Feb; 57(1):1-25. . . 2010 Jan; 54(1):173-5. . The newly licensed therapy has been approved to treat children and young adults with relapsed acute lymphoblastic leukemia. View in PubMed, Pretransplant MRD: the light is yellow, not red Blood. Choose either the "Merged" or "Side-by-Side" comparison format to specify how the two study versions are to be displayed. View in PubMed, Proceedings from the National Cancer Institute's Second International Workshop on the Biology, Prevention, and Treatment of Relapse after Hematopoietic Stem Cell Transplantation: part IIAutologous Transplantation-novel agents and immunomodulatory strategies. View in PubMed, Myelodysplastic syndrome after allogeneic hematopoietic stem cell transplantation: diagnostic and therapeutic challenges Am J Hematol. View in PubMed, Allogeneic hematopoietic stem cell transplantation for myeloproliferative disorders and myelodysplastic syndromes Hematol Oncol Clin North Am. Alan Wayne Metcalf #103334. 2009 Dec; 41(3):209-16. . View in PubMed, National Cancer Institute's First International Workshop on the Biology, Prevention, and Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation: summary and recommendations from the organizing committee Biol Blood Marrow Transplant. 2018 02 20; 115(8):E1867-E1875. . Alan S. Wayne, M.D. View in PubMed, Myeloid dysplasia and bone marrow hypocellularity in adenosine deaminase-deficient severe combined immune deficiency Blood. Give Us Feedback, Children's Center for Cancer and Blood Diseases, Five Things Parents Need to Know About CAR T-Cell Therapy for Cancer, Trained T-Cells to Target Toxic Viruses in Pediatric Patients, First Randomized Trial to Determine Most Effective, Least Toxic Treatment for Babies with Severe Combined Immunodeficiency, 4650 Sunset Blvd. 2004 Sep 15; 22(18):3798-804. . 2020 05; 67(5):e28112. View in PubMed, Simplified process for the production of anti-CD19-CAR-engineered T cells Cytotherapy. Cancer and Blood Disease Institute | Children's Hospital Los Angeles The Institute's director is Alan S. Wayne , MD, who joined CHLA and the University of Southern California (USC) in … 2015 Jan; 50(1):15-9.. View in PubMed, New frontiers in pediatric Allo-SCT: novel approaches for children and adolescents with ALL Bone Marrow Transplant. View in PubMed, Disease detection methodologies in relapsed B-cell acute lymphoblastic leukemia: Opportunities for improvement Pediatr Blood Cancer. 2010 Nov; 24(11):1859-66. . View in PubMed, Application of immunotherapy in pediatric leukemia Curr Hematol Malig Rep. 2009 Jul; 4(3):159-66. . View in PubMed, Acute GVHD in patients receiving IL-15/4-1BBL activated NK cells following T-cell-depleted stem cell transplantation Blood. View in PubMed. Is this you? is the Associate Director for Pediatric Oncology at the USC Norris Comprehensive Cancer Center, Professor of Pediatrics at the Keck School of Medicine of USC, the Director of the Children's Center for Cancer & Blood Diseases at CHLA, the Head of the Division of Hematology, Oncology and Blood & Marrow Transplantation in the Department of Pediatrics, and the Director of the Pediatric Hematology-Oncology Fellowship Training Program. View in PubMed, Immunotherapy of childhood cancer: from biologic understanding to clinical application Curr Opin Pediatr. 2011 Sep 08; 118(10):2688-94. . 2000 Oct 01; 96(7):2369-72. . View in PubMed, Hematopoietic stem cell transplantation for leukemia Pediatr Clin North Am. Programs and Services ― Alan S. Wayne, M.D. View in PubMed, Perioperative management for cholecystectomy in sickle cell disease J Pediatr Surg. Alan S Wayne's 227 research works with 5,499 citations and 10,279 reads, including: 1-s2.0-S1470204519307296-mmc1.pdf 2010 Mar 15; 16(6):1894-903. . This is a past event. 2014 Oct; 49(10):1259-65. . 2020 05 15; 26(10):2297-2307. . CHLA is the only approved center in Southern California, having played a pivotal role in the two multicenter trials leading to approval. 2011 Mar; 34(2):187-95. . View in PubMed, The American Society of Pediatric Hematology/Oncology workforce assessment: Part 1-Current state of the workforce Pediatr Blood Cancer. Get … View in PubMed, Juvenile xanthogranuloma in a child with previously unsuspected neurofibromatosis type 1 and juvenile myelomonocytic leukemia Pediatr Blood Cancer. View in PubMed, The evaluation of diagnostic tests for cancer; inhibition of serum alkaline phosphate by zinc ion; the Roche test Cancer Res. View in PubMed, Introduction to the reports from the National Cancer Institute First International Workshop on the Biology, Prevention, and Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation Biol Blood Marrow Transplant. 2018 09; 65(9):e27265. 2016 12; 22(12):2149-2154. . View in PubMed, Results from an international phase 2 study of the anti-CD22 immunotoxin moxetumomab pasudotox in relapsed or refractory childhood B-lineage acute lymphoblastic leukemia Pediatr Blood Cancer. CHLA is the only center in Southern California approved to offer CAR-T therapy to these patients. View in PubMed, NCI First International Workshop on the Biology, Prevention, and Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation: Report from the Committee on Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation Biol Blood Marrow Transplant. CHLA is one of only 32 hospitals in the country approved to treat patients with this . 2011 Jun; 52 Suppl 2:79-81. . 2018 05 21; 10(5). 2020 Jul 09; 136(2):210-223. . Alan is also one of the men responsible for the shaping and construction of Gotham City. Biol Blood Marrow Transplant. The opposite of a “one size fits all” strategy, this treatment is individually created for each patient using his or her own cells. The Therapeutic Advances in Childhood Leukemia & Lymphoma (TACL) consortium is comprised of a group of children’s hospitals and universities that work closely together to rapidly develop and carry out clinical trials. 2012; 7(12):e52655. View in PubMed, Activating signals dominate inhibitory signals in CD137L/IL-15 activated natural killer cells J Immunother. View in PubMed, Stage III neuroblastoma over 1 year of age at diagnosis: improved survival with intensive multimodality therapy including multiple alkylating agents J Clin Oncol. 2020 02; 21(2):e104-e116. 2008 Sep 17; 100(18):1271-3. . 2016 Feb; 34(1):61-5. . 2015 Feb 07; 385(9967):517-528. . 2020 11 18. . View in PubMed, Large-scale isolation and cytotoxicity of extracellular vesicles derived from activated human natural killer cells J Extracell Vesicles. Because of the challenges of giving this therapy—including cell acquisition in very ill patients and complicated management of cytokine release syndrome—only 32 designated centers in the U.S. will be initially approved to administer Kymriah. So when Alexis Bonilla was 11 years old and his disease returned for the third time, his doctor immediately referred him to CHLA. View in PubMed, Improving access to novel agents for childhood leukemia Cancer. Blood. A study version is represented by a row in the table. 1949 Nov; 9(11):681-3. . … 2017 Sep 10; 9(9). Alan Wayne, MD, and Michael Pulsipher, MD, helped . 2015 Mar; 168(6):865-73. . View in PubMed, Psychotropic medication use in pediatric patients with cancer Arch Pediatr Adolesc Med. View in PubMed, 5-Azacytidine prevents relapse and produces long-term complete remissions in leukemia xenografts treated with Moxetumomab pasudotox Proc Natl Acad Sci U S A. Virtual Event To ensure Zoom meeting security, all participants are required to register once for this series. 2007 Jan; 21(1):169-74. . View in PubMed, Bexarotene is active against subcutaneous panniculitis-like T-cell lymphoma in adult and pediatric populations Clin Lymphoma Myeloma Leuk. View in PubMed, Restricted cell surface expression of receptor tyrosine kinase ROR1 in pediatric B-lineage acute lymphoblastic leukemia suggests targetability with therapeutic monoclonal antibodies PLoS One. Team overview for Leukemia and Lymphoma Program. View in PubMed, Immunotoxin resistance via reversible methylation of the DPH4 promoter is a unique survival strategy Proc Natl Acad Sci U S A. 2013 Nov; 19(11):1534-6. . 2003 Oct; 17(5):1243-60. . 2007; 25(1):45-66. . View in PubMed, Immune-based therapeutics for pediatric cancer Expert Opin Biol Ther. Co Principal Investigators: Muller Fabbri, Ambrose Jong, Alan Wayne (CHLA); Noah Malmstadt (USC Viterbi School of Engineering) TSRI Program: Cancer and Blood Diseases Project Title: Natural Killer Cell Extracellular Vesicles for Treatment of Neuroblastoma and Leukemia . Biol Blood Marrow Transplant. 2011 May; 46(5):759-61. . The son of Solomon Wayne, Alan Wayne was living in Gotham town since his family home was considered haunted.However, sometime in the second half of the 19th century, he was walking on a bridge when … 2013 Nov; 15(11):1406-15. . View in PubMed, Nucleoside analogues in the therapy of Langerhans cell histiocytosis: a survey of members of the histiocyte society and review of the literature Med Pediatr Oncol. 2014 Jan; 20(1):4-13. . Email: wsun@chla.usc.edu. is the Associate Director for Pediatric Oncology at the USC Norris Comprehensive Cancer Center, Professor of Pediatrics at the Keck School of Medicine of USC, the Director of the Children's Center for Cancer & Blood Diseases at CHLA, the Head of the Division of Hematology, Oncology and Blood & Marrow Transplantation in the Department of Pediatrics, and the Director of the Pediatric … 2004 Feb; 44(2):229-38. . Alan S Wayne Relapse of cancer remains one of the primary causes of treatment failure and mortality after allogeneic hematopoietic stem cell transplantation (HSCT). He graduated from … Ninety percent of children diagnosed with acute lymphoblastic leukemia are cured. 2016 05; 15(5):1053-62. . 1995 Dec 29; 770:376-7. . 2012 May 01; 109(18):6898-903. . View in PubMed, Proceedings from the National Cancer Institute's Second International Workshop on the Biology, Prevention, and Treatment of Relapse after Hematopoietic Stem Cell Transplantation: introduction Biol Blood Marrow Transplant. … View in PubMed, A modified form of diphthamide causes immunotoxin resistance in a lymphoma cell line with a deletion of the WDR85 gene J Biol Chem. 2013 Nov; 37(11):1551-6. . T.J. Martell Foundation has raised more than $280 million for cancer research. View in PubMed, Pharmacokinetics of intravenous voriconazole in obese patients: implications of CYP2C19 homozygous poor metabolizer genotype Pharmacotherapy. View in PubMed, Progress in the curative treatment of childhood hematologic malignancies J Natl Cancer Inst. 2002; 4(6):539-49. . View in PubMed, Pediatric melanoma: risk factor and survival analysis of the surveillance, epidemiology and end results database J Clin Oncol. . . View in PubMed, Methylation of the DPH1 promoter causes immunotoxin resistance in acute lymphoblastic leukemia cell line KOPN-8 Leuk Res. History. 2010 Nov; 95(11):1873-9. . View in PubMed, Financial analysis of chronic transfusion for stroke prevention in sickle cell disease Blood. CHLA - Chimeric Antigen Receptor T-cell (CAR-T) Therapy The Cell Therapy Program at CHLA is led by Michael Pulsipher, MD and Alan Wayne, MD both of whom have significant expertise in CAR T-cell therapy and other cutting-edge immunotherapeutic and cell therapy approaches, having treated many patients. View in PubMed, High frequencies of leukemia stem cells in poor-outcome childhood precursor-B acute lymphoblastic leukemias Leukemia. Fatal capillary leak syndrome in a child with acute lymphoblastic leukemia treated with moxetumomab pasudotox for pre-transplant minimal residual disease reduction Pediatr Blood Cancer. “I am writing to offer my strongest possible recommendation in support of Caleb Moss” “I am the physician in charge of the pediatric cancer and blood diseases program at Children’s Hospital Los Angeles (CHLA) and the University of Southern California. Dear friends and family, After couple of years of participating in the biking portion of the Nautica Malibu Triathlon, I decided to run the classic distance course this year (1/2 mile swim, 17 miles bike, 4 mile run; which is making Mushi very nervous ☺). . new therapy. Coronavirus Update; ... Dr. Alan Stuart Wayne, MD. 2006 Apr; 12(4):375-96. . 2015 Mar; 2(3):e87-8.. View in PubMed, T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial Lancet. View in PubMed, Mass spectrometric quantification of asparagine synthetase in circulating leukemia cells from acute lymphoblastic leukemia patients J Proteomics. Biol Blood Marrow Transplant. 1995 Jan 01; 85(1):21-30. . He has been in practice for more than 20 years. The U.S. Food and Drug Administration recently approved a novel cancer treatment that resulted in patients with resistant leukemia going into remission, and the majority remaining cancer free after a year. 2012 Jul 12; 120(2):244-6. . View in PubMed, Desferrioxamine provocative test: methodology for estimating iron and total iron binding capacity Blood. He graduated with honors from Northwestern University Medical School in 1984. Director, Graduate Medical Education & Designated Institutional Official, Children's Hospital Los Angeles Attending Physician; Hematology, Oncology and Blood and Marrow Transplantation Professor of Clinical Pediatrics (Educational Scholar) Weili Sun, Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, Keck School of Medicine, USC‐Norris Comprehensive Cancer Center, University of Southern California, 4650 Sunset Boulevard, MS#54, Los Angeles, CA 90027. View in PubMed, Reduced-intensity allogeneic stem cell transplantation in children and young adults with ultrahigh-risk pediatric sarcomas Biol Blood Marrow Transplant. CHLA - wrote - Team CHLA is fundraising for our pediatric cancer research program as part of the Nautica Malibu Triathlon. One each from columns A and B. View in PubMed, Anti-CD22 immunotoxin RFB4(dsFv)-PE38 (BL22) for CD22-positive hematologic malignancies of childhood: preclinical studies and phase I clinical trial Clin Cancer Res. Dr. Alan Wayne, CHLA, and Helen Wayne attend The T.J. Martell Foundation 43rd New York Honors Gala at Cipriani 42nd Street on October 15, 2018 in New York City. 2013 Nov; 19(11):1537-45. . 2012 May; 18(5):698-707. . 2010 May; 16(5):563-4. . View in PubMed, Phase 1 study of the anti-CD22 immunotoxin moxetumomab pasudotox for childhood acute lymphoblastic leukemia Blood. Get appointment information and hours of operation for Alan Wayne, practicing Hematology/Oncology doctor in Los Angeles, CA. View in PubMed, The American Society of Pediatric Hematology/Oncology workforce assessment: Part 2-Implications for fellowship training Pediatr Blood Cancer. View in PubMed, Protein Kinase Inhibitor H89 Enhances the Activity of Pseudomonas Exotoxin A-Based Immunotoxins . View in PubMed, Investigating the biology of relapsed acute leukemia: Proceedings of the Therapeutic Advances for Childhood Leukemia & Lymphoma (TACL) Consortium Biology Working Group Pediatr Hematol Oncol. View in PubMed, Impact of bone marrow transplantation for symptomatic sickle cell disease: an interim reportMulticenter investigation of bone marrow transplantation for sickle cell disease. 2018 03 08; 131(10):1145-1148. . 1999 Nov; 33(5):476-81. . For more information, please contact our New Referrals Office. View in PubMed, Outcome of children with multiply relapsed B-cell acute lymphoblastic leukemia: a therapeutic advances in childhood leukemia & lymphoma study Leukemia. View in PubMed, Gene therapy for adenosine deaminase-deficient severe combined immune deficiency: clinical comparison of retroviral vectors and treatment plans Blood. 2010 Feb; 22(1):2-11. . 2012 Nov 01; 120(18):3635-46. . Please help Team CHLA by supporting our fundraising efforts with a donation. Dr. Alan Wayne, MD is a Pediatric Hematology-Oncology Specialist in Los Angeles, CA and has over 36 years of experience in the medical field. The approach is called CAR-T therapy, and it uses a patient’s own white blood cells that have been genetically re-engineered to specifically target and kill cancer cells. Existing Patients or Family Members: 323-361-4624, New Patients, Referrals and 2nd Opinions: 323-361-4100, About Our Hospital Amount Raised $26,281 License Status: Active Address: Patterson Law Firm, APC, 1800 E Imperial Hwy Ste 110, Brea, CA 92821 County: Orange County Phone Number: (714) 441-1410 Fax Number: (714) 332-8397 Email: furimkf@dogsd. View in PubMed, Anti-CD22-chimeric antigen receptors targeting B-cell precursor acute lymphoblastic leukemia Blood. 2013 Apr 26; 288(17):12305-12. . 2010 Nov; 16(11):1467-503. . Find a Doctor Pat Levitt 2008 Apr 30; 71(1):61-70. . 2017 Sep - Oct; 34(6-7):355-364. . On behalf of the Ford Theodore Miller Murphy Family, Emmy-Award winning writer, producer and director Ryan Murphy and his husband, photographer David Miller, have made a landmark $10 million gift to Children's Hospital Los Angeles (Chla). Keck School ranks 30th in research in U.S. News & World Report’s 2020 "Best Graduate Schools" rankings. Getting Here However, of those who relapse, only a minority survive long-term. 2011 Apr; 17(4):443-54. . 2014 Jul; 20(7):1000-7. . View in PubMed, A phase 1 study of azacitidine combined with chemotherapy in childhood leukemia: a report from the TACL consortium Blood. Alexis’ blood was collected and sent to the lab so that his T-cells could be genetically engineered to recognize and destroy leukemia cells. 1993 Jan; 11(1):84-90. . advancement. 2001 Jun; 138(6):939-41. . View in PubMed, Enhancing immunotoxin cell-killing activity via combination therapy with ABT-737 Leuk Lymphoma. View in PubMed, Immunotoxins for leukemia Blood. . . Humanities, Ethics/Economics, Arts and the Law (HEAL) Program, Grant & Contract Proposal Preparation Toolbox, Post Doctorial Individual Development Plan, Institutionally-Limited Grants Opportunities, Keck School of Medicine Governance Document, Keck School of Medicine Standing Committees. 2020 04; 67(4):e28149. View in PubMed, Bone marrow homing and engraftment of human hematopoietic stem and progenitor cells is mediated by a polarized membrane domain Blood. 2012 Feb; 12(1):20-5. . 2015 Jun 15; 121(12):1927-36. . Make an Appointment View in PubMed, Myeloid lineage switch following chimeric antigen receptor T-cell therapy in a patient with TCF3-ZNF384 fusion-positive B-lymphoblastic leukemia Pediatr Blood Cancer. View in PubMed, Biological roles and potential applications of immune cell-derived extracellular vesicles J Extracell Vesicles. Bone Marrow Transplant. 2013; 3:166. . 2019; 8(1):1588538. . The event takes place on Sunday, September 16, 2018, and we have committed to raise at least $250,000 for Children’s Hospital Los Angeles in partnership with the event. 4650 W Sunset Blvd. View in PubMed, Cytotoxicity of the anti-CD22 immunotoxin HA22 (CAT-8015) against paediatric acute lymphoblastic leukaemia Br J Haematol. “I am the physician in charge of the pediatric cancer and blood diseases program at Children’s Hospital Los Angeles (CHLA) and the University of Southern California. View in PubMed, Multicentric dermatofibrosarcoma protuberans in patients with adenosine deaminase-deficient severe combined immune deficiencyJ Allergy Clin Immunol. 2014 Jul; 20(7):1033-9. . View in PubMed, Children as hematopoietic cell donors in research: when is it approvable? View in PubMed, Long-term remission in a child with refractory EBV(+) hydroa vacciniforme-like T-cell lymphoma through sequential matched EBV(+)-related allogeneic hematopoietic SCT followed by donor-derived EBV-specific cytotoxic T-lymphocyte immunotherapy Bone Marrow Transplant. . . That figure grew even higher Tuesday night (Oct. 2) at its annual Spirit of Excellence dinner in Los Angeles Alan Wayne is Bruce Wayne's great-great-grandfather and first born generation in Gotham. 1990 Nov 15; 76(10):2162. . As the head of the division, Dr. Wayne oversees the research, clinical and education programs in pediatric hematology, oncology and hematopoietic stem cell transplantation within USC and CHLA. View in PubMed, Elevation of soluble CD307 (IRTA2/FcRH5) protein in the blood and expression on malignant cells of patients with multiple myeloma, chronic lymphocytic leukemia, and mantle cell lymphoma Leukemia. Alan S. Wayne, M.D. 2012 Nov 01; 30(31):3876-83. . TACL develops phase I /II clinical trials of new therapies and novel therapy combinations in recurrent childhood leukemia and lymphoma. 2012 Feb 23; 119(8):1848-55. . . View in PubMed, Monoclonal antibody-based therapies: a new dawn in the treatment of acute lymphoblastic leukemia J Clin Oncol. Alan S. Wayne, MD, is the Director of the Children’s Center for Cancer and Blood Diseases at Children’s Hospital Los Angeles and serves as head of the Division of Hematology, Oncology and Blood and Marrow Transplantation in the Department of Pediatrics. Before leading the Institute at Children’s Hospital Los Angeles, he served for 14 years as clinical directors of the Pediatric Oncology Branch of the National Cancer Institute (NCI) at the National Institutes of Health (NIH). 2016. 2012 Mar; 129(3):762-769. e1. View in PubMed, Extracellular vesicles derived from natural killer cells use multiple cytotoxic proteins and killing mechanisms to target cancer cells J Extracell Vesicles. . 2010 Oct; 16(10):1325-46. . Of CYP2C19 homozygous poor metabolizer genotype Pharmacotherapy ( CAR ) T-cell therapy in a child with lymphoblastic! Disease reduction Pediatr Blood Cancer J Haematol pediatric sarcomas Biol Blood marrow.! Methodology for estimating iron and TOTAL iron binding capacity Blood, Integrin mediates. All participants are required to register once for this series ):5835-49. future Biol... And therapeutic challenges Am J Hematol search for more papers by this author ― Alan Wayne... The table Methylation of the surveillance, epidemiology alan wayne chla end results database J Clin Oncol of only hospitals... Extracorporeal photo-apheresis for the third time, his doctor immediately referred him to chla:3876-83.. 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